Isotretinoin and Long-term Antibiotic Use and Multiple Sclerosis

    Basic Details
    Date Posted
    Thursday, June 30, 2016
    Status
    Complete
    Medical Product
    abacavir
    doxycycline
    erythromycin
    isotretinoin
    lamivudine
    long-term antibiotic
    minocycline
    zidovudine
    Health Outcome(s)
    multiple sclerosis
    Description

    Report 1 is a modular program-based one-time assessment of isotretinoin and long-term antibiotics, including doxycycline, minocycline, and erythromycin, and subsequent multiple sclerosis (MS) diagnoses. Report 2 is a modular program-based one-time assessment of multiple sclerosis diagnoses as defined in three different ways. The queries were run against the Mini-Sentinel Distributed Database (MSDD) for the time period of January 1, 2000 to May 31, 2013.  Modular programs are adaptable standardized programs. Results were generated using Modular Program 3; click here for more information.  Queries were distributed in July 2014. This report includes data from 17 Data Partners.
     
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    Additional Details
    FDA Center
    CDER
    Time Period
    January 1, 2000 - May 31, 2013
    Study Type
    Modular Program
    Assessment Type
    Exploratory Analyses
    Data Sources
    Mini-Sentinel Distributed Database (MSDD)