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Maintaining and Expanding the Reach of the Sentinel EHR and Claims Network (DI8)

    Basic Details
    Date Posted
    Status
    Complete
    Description

    Health Information Exchanges (HIEs) provide the capability to electronically move healthcare data across multiple data streams. Electronic Health Records (EHRs) from academic medical centers and commercial data aggregators typically lack data when patients receive out-of-system care. HIEs offer great potential in comprehensively characterizing longitudinal care patterns across data streams from insurance claims and EHRs regardless of care settings, which can be viewed as a major strength when conducting unbiased pharmacoepidemiologic investigations. 

    Through this project, the Innovation Center will undertake the following aims: 

    1) Identify viable HIE sources to support fulfillment of the Real-World Evidence Data Enterprise (RWE-DE) mandate via a review of major state and regional HIEs to identify exchanges that are most mature in their data infrastructure and ready for Sentinel specific use cases. 

    2) Partner with one HIE with a standing EHR-claims linkage covering a population of at least 2 million on conducting a high-level data characterization exercise. Through this effort, the IC plans to efficiently scale a network of HIEs for use by the Sentinel system, provide recommendations as well as outline challenges to incorporating HIEs into the Sentinel system.

    Information
    Time Period
    09/30/2023-05/31/2024
    Data Source(s)
    MyHealth Access Network
    Workgroup Leader(s)

    Rishi Desai, MS, PhD; Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 

    Anjum Khurshid, MD, PhD; Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA

    Sarah Dutcher, MS, PhD; US Food and Drug Administration, Silver Spring, MD

    Workgroup Member(s)

    Trish Bright, PhD; Tiffany Austin, MSPH; Youjin Wang, PhD; US Food and Drug Administration, Silver Spring, MD

    Sebastian Schneeweiss, MD, ScD; Haritha Pillai, MPH; Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA  

    Eliel Oliveira, MBA, MSc, FAMIA; Meighan Rogers Driscoll, MPH; Alexis Jaquish; Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA

    Patrick J. Heagerty, MS, PhD; University of Washington, Seattle, WA

    Michael E. Matheny, MD, MS, MPH, FACMI; Vanderbilt University Medical Center, Nashville, TN

    David Kendrick, MD, MPH, FACP; Obiageli Obinwanne, MHA, PMP; Jenny Sun, PhD; Joe Walker, MSIE, CISSP; MyHealth Access Network, Tulsa, OK