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Mini-Sentinel: Two-Dimensional Scan Statistics for Assessing Vaccine Safety in Pregnancy (PRISM)

Basic Details
Date Posted
Status
Complete
Description

Methods project including two simulation studies to: 

  1. Evaluate the performance of (1-dimensional) temporal scan statistics under various scenarios, and
  2. evaluate the performance of a 2-dimensional temporal scan statistic under alternative assumptions about pregnancy outcomes
Deliverable(s) (1)
Evaluation of Scan Statistics for Assessing Vaccine Safety in Pregnancy
Information
Data Source(s)
Mini-Sentinel Distributed Database (MSDD)
Workgroup Leader(s)

Lingling Li, PhD; Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA

Wei Hua, MD, PhD; Lihan Yan PhD; Center for Biologics Evaluation and Research, FDA, Silver Spring, MD 

Workgroup Member(s)

Sophia Axtman; Sandra Feibelmann, MPH; Alison Kawai ScD; Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA

Gabriela Vazquez Benitez, PhD, MSc; HealthPartners Institute for Education and Research, Minneapolis, MN 

Stan Xu, PhD; Kaiser Permanente Institute for Health Research, Colorado, Denver, CO