Descriptive Analysis of Long- And Intermediate-Acting Insulin and Key Safety Outcomes in Adults With Type 2 Diabetes Mellitus

    Details
    Basic Details
    Date
    Monday, August 12, 2019
    Entity
    BBCIC
    Type
    Publication
    Description

    As new biosimilar and follow-on insulins enter the market, more data are needed on safety, effectiveness, and patterns of use for these products to inform prescriber and patient decision-making regarding treatment. Additionally, data are needed regarding real-world patterns of use to inform future studies comparing the safety and effectiveness of biosimilars to already approved agents for diabetes treatment. The objective of this study was to analyze the medication use patterns, adverse events, and availability of glycated hemoglobin (A1c) values for adult patients with type 2 diabetes mellitus (T2DM) who use long-acting insulin (LAI) or neutral protamine Hagedorn (NPH), an intermediate-acting insulin. We used the Biologics and Biosimilars Collective Intelligence Consortium's (BBCIC) distributed research network (DRN) for this descriptive analysis.

    Contributors
    Author(s)

    Daniel J. Kent, Cheryl N. McMahill-Walraven, Catherine A. Panozzo, Pamala A. Pawloski, Kevin Haynes, James Marshall, Jeffrey Brown, Bernadette Eichelberger, Catherine M. Lockhart