Incidence of Statin Use in Older Adults With and Without Cardiovascular Disease and Diabetes Mellitus, January 2008 - March 2018

    Details
    Basic Details
    Date
    Thursday, December 5, 2019
    Entity
    NIH
    Type
    Publication
    Description

    Data from randomized controlled trials and observational studies on older adults who take statins for primary prevention of atherosclerotic cardiovascular disease are limited. To determine the incidence of statin use in older adults with and without cardiovascular disease (CVD) and/or diabetes (DM), we conducted a descriptive observational study. The cohort consisted of health plan members in the National Institutes of Health (NIH) Collaboratory Distributed Research Network aged >75 years who had continuous drug and medical benefits for ≥183 days during the study period, January 1, 2008 - March 31, 2018. We defined DM and CVD using diagnosis codes, and identified statins using dispensing data. Statin use was considered incident if a member had no evidence of statin exposure in the claims during the previous 183 days, and the use was considered long-term if statins were supplied for ≥180 days. Incidence rates were reported among members with and without CVD and/or diabetes, and stratified by year, sex, and age group.

    Contributors
    Author(s)

    Catherine A. Panozzo, Lesley H. Curtis, James Marshall, Lawrence Fine, Barbara L. Wells, Jeffrey S. Brown, Kevin Haynes, Pamala A. Pawloski, Adrian F. Hernandez, Sarah Malek, Beth Syat, Richard Platt