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2022 Sentinel Public Training Day: Inverse Probability of Treatment Weighting & Innovation Day 

Event Information
Date
Event Type
Training
Event Location
Virtual
Description

The 2022 Sentinel Public Training and Innovation Day took place over two days in April. 

 

2022 Sentinel Public Training Day: Inverse Probability of Treatment Weighting

The 2022 Sentinel Public Training Day focused on Inverse Probability of Treatment Weighting (IPTW), an analytic method that can reduce confounding bias in observational studies of medical treatments. Investigators from the Sentinel Operations Center also discussed opportunities presented by the new IPTW tool within the Sentinel Routine Querying System, the new Sentinel Views dashboard component, and how researchers can conduct analyses of routinely collected electronic health data in the Sentinel Common Data Model format.

 

2022 Sentinel Innovation Day

The 2022 Sentinel Innovation Day focused on challenges and opportunities in integrating electronic health record-based data in common data models, computable phenotyping to aid medical product safety investigations, advanced analytic approaches to improve confounding adjustments in Sentinel investigations, and a causal inference framework for Sentinel.

 

Event Materials

Presentations

Webcasts

 

Information
Host

U.S. Food and Drug Administration, Sentinel Operations Center, and Sentinel Innovation Center

 

Related Assessment(s)
Sentinel Drug Analysis: Thromboembolic Stroke, Major Extracranial Bleeding, Gastrointestinal Bleeding, and Intracranial Hemorrhage following Direct Oral Anticoagulant Use: An Inverse Probability of Treatment Weighting Analysis
Presenter(s)

The Sentinel Public Training featured the following speakers:

  • John Connolly, ScD
  • Xiaojuan Li, PhD, MSPH
  • Jenn Lyons, PhD, MPH

Innovation Day featured the following speakers:

  • Keith Marsolo, PhD, Duke University School of Medicine
  • Jennifer Nelson, PhD, Kaiser Permanente Washington Health Research Institute
  • David Carrell, PhD, Kaiser Permanente Washington Health Research Institute
  • Adrian Cosmin Bejan, PhD, Vanderbilt University Medical Center
  • Joshua Smith, PhD, Vanderbilt University Medical Center
  • Richard Wyss, PhD, Mass General Brigham
  • Rishi Desai, PhD, Mass General Brigham