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Association of COVID-19 vs Influenza with Risk of Arterial and Venous Thrombotic Events Among Hospitalized Patients

    Basic Details

    The incidence of arterial thromboembolism and venous thromboembolism in persons with COVID-19 remains unclear. The objective of this study was to measure the 90-day risk of arterial thromboembolism and venous thromboembolism in patients hospitalized with COVID-19 before or during COVID-19 vaccine availability vs patients hospitalized with influenza. The authors conducted a retrospective cohort study of 41,443 patients hospitalized with COVID-19 before vaccine availability (April-November 2020), 44,194 patients hospitalized with COVID-19 during vaccine availability (December 2020-May 2021), and 8,269 patients hospitalized with influenza (October 2018-April 2019) in the US Food and Drug Administration Sentinel System (data from two national health insurers and four regional integrated health systems).


    Vincent Lo Re III, Sarah K. Dutcher, John G. Connolly, Silvia Perez-Vilar, Dena M. Carbonari, Terese A. DeFor, Djeneba Audrey Djibo, Laura B. Harrington, Laura Hou, Sean Hennessy, Rebecca A. Hubbard, Maria E. Kempner, Jennifer L. Kuntz, Cheryl N. McMahill-Walraven, Jolene Mosley, Pamala A. Pawloski, Andrew B. Petrone, Allyson M. Pishko, Meighan Rogers Driscoll, Claudia A. Steiner, Yunping Zhou, Noelle M. Cocoros

    Corresponding Author

    Vincent Lo Re III; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA