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Chart Validation of Inpatient ICD-9-CM Administrative Diagnosis Codes for Ischemic Stroke Among IGIV Users in the Sentinel Distributed Database

    Basic Details

    The Sentinel Distributed Database (SDD) is a large database of patient-level medical and prescription records, primarily derived from insurance claims and electronic health records, and is sponsored by the U.S. Food and Drug Administration for drug safety assessments. In this chart validation study, the authors report on the positive predictive value (PPV) of inpatient International Classification of Diseases, Ninth Edition, Clinical Modification (ICD-9-CM) codes for acute ischemic stroke (AIS) and administrative diagnosis codes (433.x1, 434.xx, and 436) in the SDD.


    Eric M. Ammann MS, Enrique C. Leira MD, MS, Scott K. Winiecki MD, Nandakumar Nagaraja MD, MS, Sudeepta Dandapat MD, Ryan M. Carnahan PharmD, MS, BCPP, Marin L. Schweizer PhD, James C. Torner PhD, Candace C. Fuller PhD, Charles E. Leonard PharmD, MSCE, Crystal Garcia MPH, Madelyn Pimentel, Elizabeth A. Chrischilles PhD, MS

    Corresponding Author

    E. M. Ammann, CPHB S400, 145 North Riverside Drive, The University of Iowa, Iowa City, IA 52242. Email: