Opioid Tolerance and Urine Drug Testing among Initiates of Extended-Release or Long-Acting Opioids in Food and Drug Administration's Sentinel System

    Basic Details
    Date
    Monday, November 20, 2017
    Type
    Publication
    Medical Product
    extended-release and long-acting (ER/LA) opioid analgesic
    opioid
    Description

    A risk evaluation and mitigation strategy for extended-release and long-acting (ER/LA) opioid analgesics was approved by the Food and Drug Administration in 2012. The authors' objective was to assess frequency of opioid tolerance and urine drug testing for individuals initiating ER/LA opioid analgesics.

    Information
    Time Period
    January 1, 2009 – December 31, 2013
    Population / Cohort
    All individuals 0-64 years of age
    Data Source(s)
    Mini-Sentinel Distributed Database (MSDD)
    Author(s)

    Marc R. Larochelle MD, MPH; Noelle M. Cocoros DSc, MPH; Jennifer Popovic DVM, MA; Elizabeth C. Dee MPH; Cynthia Kornegay PhD; Jing Ju PharmD, PhD; Judith A. Racoosin MD, MPH