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Switching Patterns of Immediate-Release Forms of Generic Mixed Amphetamine Salts Products Among Privately and Publicly Insured Individuals Aged 15-64 Years in the United States, 2013-2019

    Basic Details

    Immediate-release forms of generic mixed amphetamine salts (MAS) have been the subject of passive surveillance reports signaling lack of effectiveness. We examined switching patterns that might suggest whether long-term users of specific MAS are more likely to switch away or switch back after use of the MAS of interest in the FDA's Sentinel Distributed Database (SDD).

    We required at least 60-day continuous supply of selected MAS grouped by Abbreviated New Drug Application (ANDA) to describe patterns of switching away from and to generics approved under the ANDAs of interest among individuals ages 15-64 years with attention deficit hyperactivity disorder or narcolepsy during 2013-2019.


    Silvia Perez-Vilar, Maria E. Kempner, Sarah K. Dutcher, Talia J. Menzin, Corinne Woods, Kira Leishear, James Osterhout, Sruthi Adimadhyam, Modupeola Adereti, Amanda Carruth, Aaron Hansbury, Sukhminder K. Sandhu, Jennifer G. Lyons

    Corresponding Author

    Silvia Perez-Vilar, Office of Surveillance and Epidemiology, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA