Who Gets Treated for Influenza: A Surveillance Study From the US Food and Drug Administration’s Sentinel System

This study describes the baseline characteristics and complications of individuals with influenza in the US FDA’s Sentinel System by antiviral treatment timing.

We identified the comorbidities, vaccination history, influenza testing, and outpatient antiviral dispensings of individuals with influenza using administrative claims data from 13 Data Partners including the Centers for Medicare and Medicaid Services, integrated delivery systems, and commercial health plans. We assessed complications within 30 days: hospitalization, oxygen use, mechanical ventilation, critical care, ECMO, and death.