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Anti-Obesity Medications (Benzophetamine, Bupropion/Naltrexone, Diethylpropion, Liraglutide, Lorcaserin, Orlistat, Phendimetrazine, Phentermine, Phentermine/Topiramate) & Duration of Use and Patient Characteristics

    Basic Details
    Last Updated
    Wednesday, July 26, 2023
    Original Posting Date
    Health Outcome(s)
    duration of use
    patient characteristics
    Drug Use
    Meets requirements of FD&C Act Sec 505(o) prior to requiring a PMR
    Regulatory Determination / Use

    The Bipartisan Budget Act of 2018 (P.L. 115-123) included a provision for the Government Accountability Office (GAO) to review the prevalence of obesity and the use of obesity drugs. GAO requested that FDA assess utilization patterns and treatment duration for the nine available prescription used to treat obesity. FDA used the Sentinel System to assess the baseline characteristics of patients initiating weight management drugs and evaluate the duration of treatment of the first treatment episode and cumulative duration across all treatment episodes. These results were incorporated into the GAO report entitled, “Few Adults Used Prescription Drugs for Weight Loss and Insurance Coverage Varied.”