Adherence to Absolute Neutrophil Count (ANC) Monitoring Recommendations Following Clozapine Use: Second Descriptive Analysis

This analysis examined adherence to FDA's Risk Evaluation and Mitigation Strategy (REMS) absolute neutrophil count (ANC) monitoring recommendations among clozapine users in the Sentinel Distributed Database (SDD). This analysis differs from the first descriptive analysis by updating some definitions of adherence. 

We distributed this request to seven Sentinel Data Partners on August 15, 2022. This analysis contains three reports.

• Report 1 contains all data returned by Data Partners. The study period includes data from January 1, 2010 to October 31, 2021.
• Reports 2 contains data from members with Medicaid/Children's Health Insurance Program (CHIP). The study period includes data from October 1, 2015 to December 31, 2019.
• Report 3 contains data from members with Medicare Fee-For-Service (FFS). The study period includes data from October 1, 2015 to December 31, 2019.