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Non-Melanoma Skin Cancer following Hydrochlorothiazide Use

    Basic Details
    Date Posted
    Medical Product
    bendroflumethiazide (BFMTZ)
    chlorothiazide (CTZ)
    hydrochlorothiazide (HCTZ)
    Health Outcome(s)
    non-melanoma skin cancer

    The goal of this request was to investigate the occurrence of non-melanoma skin cancer (NMSC) diagnoses among incident users of thiazide diuretics or comparator drugs of interest and to observe follow-up time after incident drug dispensing in the Sentinel Distributed Database (SDD). Data from January 1, 2000 to October 31, 2017 from 17 Data Partners contributing to the SDD were included in this report.

    Additional Details
    FDA Center
    Time Period
    January 1, 2000 - October 31, 2017
    Analysis Type
    Population / Cohort
    All individuals
    Data Sources
    Sentinel Distributed Database (SDD)