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Stroke, Gastrointestinal Bleeding, and Intracranial Hemorrhage Following Apixaban or Warfarin Use in Patients with Non-Valvular Atrial Fibrillation: A Propensity Score Matched Analysis

    Basic Details
    Date Posted
    Medical Product
    Health Outcome(s)
    gastrointestinal (GI) bleed
    intracranial hemorrhage

    This analysis investigates the risk of stroke, gastrointestinal bleeding, and intracranial hemorrhage for patients with non-valvular atrial fibrillation treated with apixaban compared to warfarin in the Sentinel Distributed Database.

    The study period included data from December 28, 2012 to June 30, 2018. We distributed this request to 8 Data Partners on January 22, 2019. This request includes two reports:

    • Report 1: In this report, analyses were restricted to Data Partners 1-7 of 8.
    • Report 2: In this report, analyses were restricted to Data Partner 8 of 8.

    The analytic package associated with this analysis can be found externally in Sentinel's Git Repository located here. The Git Repository serves as Sentinel's version control tracking system for analytic packages and technical documentation.