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Utilization of Amyloid Beta-Directed Monoclonal Antibodies: A Descriptive Analysis

    Basic Details
    Date Posted
    Status
    Complete
    Medical Product
    amyloid beta-directed monoclonal antibodies
    Description

    In this report, we assessed utilization of three monoclonal antibody (mAB) drugs within the Sentinel Distributed Database (SDD): lecanemab, aducanumab, and donanemab. We also quantified how often the mABs of interest were used concomitantly with other drugs and drug classes. The study period included data from June 7, 2021 to May 31, 2024.

    We distributed this request to six Sentinel Data Partners on January 27, 2025. These six Data Partners are a subset of the SDD. Data from Medicare patients having both fee‐for‐service medical coverage and Part D drug coverage are included.

    Additional Details
    FDA Center
    CDER
    Time Period
    June 7, 2021 - May 31, 2024
    Analysis Type
    Descriptive
    Population / Cohort
    Individuals 30 years of age and older
    Data Sources
    Sentinel Distributed Database (SDD)