Details
In this report, we examined counts of individuals and total available follow-up time for users of guselkumab, risankizumab, and tildrakizumab with plaque psoriasis and users of brodalumab in the Sentinel Distributed Database (SDD). This is the third report of an ongoing plan to monitor uptake of these drugs until sufficient follow-up time accrues among treated patients to conduct propensity-score-matched analyses examining non-Hodgkin lymphoma in users of guselkumab, risankizumab, and tildrakizumab versus users of a comparator drug, as well as serious infection, acute myocardial infarction/stroke, and inpatient neutropenia in users of brodalumab versus users of a comparator drug.
- The first monitoring analysis for guselkumab, risankizumab, and tildrakizumab can be found here.
- The first monitoring analysis for brodalumab can be found here.
- The second monitoring analysis for guselkumab, risankizumab, tildrakizumab, and brodalumab can be found here.
The study period includes data from February 15, 2017 to January 31, 2024. We distributed this request to six Sentinel Data Partners on July 9, 2024.