Valganciclovir Use in Children with Congenital Cytomegalovirus Disease (cCMV) or Cytomegalovirus (CMV) Infection: A Descriptive Analysis

This analysis includes two reports:

• Report 1: We examined the trends in diagnosis of congenital cytomegalovirus disease (cCMV) or cytomegalovirus infection (CMV). We also assessed clinical characteristics, laboratory tests performed for CMV diagnosis, hearing loss and hematologic outcomes among infants with CMV and those who used valganciclovir/ganciclovir treatment.
• Report 2: We assessed follow-up time and distribution of valganciclovir or ganciclovir treatment in infants with cCMV. We also assessed clinical characteristics, laboratory tests performed for CMV diagnosis, hearing loss and hematologic outcomes among infants with CMV who used valganciclovir/ganciclovir treatment. 

The study period includes data from January 1, 2008 through May 31, 2021. We distributed this request to 12 Sentinel Data Partners on December 9, 2021.