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Evaluation of Confounding Control in Estimations of Influenza Antivirals Use and Influenza Complications: A Propensity Score Matched Analysis

    Basic Details
    Date Posted
    Status
    Complete
    Medical Product
    influenza antivirals
    Health Outcome(s)
    all-cause hospitalization
    fracture
    pneumonia
    respiratory antibiotic use
    Description

    In this request, we evaluated the presence of residual confounding and estimated the association between oseltamivir and select influenza complications during the 1‐30 days after influenza diagnosis, separately during the 61‐90 days after diagnosis (i.e., negative control period), and using a negative control endpoint during the 2014‐2015 influenza season. We distributed this request to Sentinel Data Partners on December 9, 2019. This request includes three reports, each analyzing a different influenza season:

    • Report 1: contains results for the 2014-2015 influenza season. The study period includes data from October 1, 2014 through April 30, 2015 and 11 Sentinel Data Partners contributed to this report.
    • Report 2: contains results for the 2015‐2016 influenza season. The study period includes data from October 1, 2015 to April 30, 2016 and nine Sentinel Data Partners contributed to this report.
    • Report 3: contains results for the 2016‐2017 influenza season. The study period includes data from October 1, 2016 through April 30, 2017 and 11 Sentinel Data Partners contributed to this report.
    Additional Details
    Time Period
    October 1, 2014 - April 30, 2015; October 1, 2015 - April 30, 2016; October 1, 2016 - April 30, 2017
    Analysis Type
    Retrospective Inferential
    Population / Cohort
    Individuals 18 years of age and older
    Data Sources
    Sentinel Distributed Database (SDD)