Skip to main content

Trends in Single-Dose Doxycycline for Lyme Disease Prophylaxis in the United States: An Updated Descriptive Analysis

    Basic Details
    Date Posted
    Status
    Complete
    Medical Product
    doxycycline
    Description

    Lyme disease can be prevented by taking one dose of doxycycline (200 mg or 4.4 mg/kg for persons <45 kg) when administered within 72 hours after a high‐risk tick bite. To shed light on patterns of Lyme disease post‐exposure prophylaxis (PEP) in the United States, we characterized the frequency and patterns of single dose doxycycline over time, and described characteristics of individuals with these dispensings in the Sentinel Distributed Database (SDD). This a follow up to a previous analysis to update the study period and include categories for zip code mapping to multiple urban categories.

    The study period includes data from January 1, 2010 to December 31, 2020. We distributed this request to five Sentinel Data Partners on July 8, 2022.